Cheap flights from San Francisco to Santiago
Travel > South America > Chile > San Francisco to Santiago flights
Travel tip: I was there 5 years ago, the people is werry friendly, they make you part of their family, is so hard to forget people like them!Check our current prices for flights from San Francisco to Santiago. Please note that we also give you historical search data for this city connection. These are all airfares that people found in the past, in order to find more current flight information from San Francisco to Santiago, you will need to run a search below.
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Cheap Santiago airfares from $851/RT are provided by Cheapoair.com. Outbound flight is leaving on 03/25/2025, 11:57 am from San Francisco Intl (SFO) airport and arrives at Santiago Pudahuel (SCL) at 06:20 am. The flight time is 18 hours and 23 minutes. The Returning flight departes on 04/15/2025, 08:40 pm (other return dates are also available). Date posted: 14 Feb 2025
Price evolution for flights From San Francisco To Santiago

Recent Deals on Flights from San Francisco to Santiago:Roundtrip / Oneway
- $851
Lan Airlines
cheapoair.com check priceFrom To Departure Time San Francisco, CA (SFO) Santiago, CL (SCL) 03/25/2025 11:57 am Santiago, CL (SCL) San Francisco, CA (SFO) 04/15/2025 08:40 pm - $934
Multiple Airlines
cheapoair.com check priceFrom To Departure Time San Francisco, CA (SFO) Santiago, CL (SCL) 03/25/2025 11:54 pm Santiago, CL (SCL) San Francisco, CA (SFO) 04/15/2025 09:35 pm - $989
Lan Airlines
cheapoair.com check priceFrom To Departure Time San Francisco, CA (SFO) Santiago, CL (SCL) 07/02/2025 01:00 pm Santiago, CL (SCL) San Francisco, CA (SFO) 07/08/2025 08:40 pm - $1437
Multiple Airlines
cheapoair.com check priceFrom To Departure Time San Francisco, CA (SFO) Santiago, CL (SCL) 07/02/2025 02:30 am Santiago, CL (SCL) San Francisco, CA (SFO) 07/08/2025 08:40 pm - We are sorry but currently there are no oneway offers for flights from San Francisco to Santiago.
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Know what to do when flying to Santiago?
Santiago Travel Guide Santiago is the capital of Chile. It is one of the most populous cities in South America. Santiago has been a favorite destination for the travelers for its beautiful landscapes, archeological wonders, shopping malls and high-rise architecture. [...]Santiago History Santiago is the capital city of Chile. It was founded by conquistador Pedro de Valdivia in 1541. By the 16th century, Santiago was inhabited by a few thousand. It was selected capital in 1818. The city of Santiago was destroyed and built many [...]
Santiago Sightseeing Santiago is a beautiful city of Chile. It is located in the central valley of the country known as Santiago Basin. Santiago Basin is a large bowl-shaped valley surrounded by the mountains. Due to the continued economic growth for almost [...]
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