Cheap flights from San Francisco to Santo Domingo

Travel > Caribbean > Dominican Republic > San Francisco to Santo Domingo flights

Travel tip: Santo Domingo is one of the oldest cities in the New World. You can see here the first hospital and the first cathedral. Walking in the city you can also admire the Spanish colonial architecture. Santo Domingo is the most bustling and diverse city in the Caribbean with the greatest variety of restaurants, night life and shopping opportunities.

Check our current prices for flights from San Francisco to Santo Domingo. Please note that we also give you historical search data for this city connection. These are all airfares that people found in the past, in order to find more current flight information from San Francisco to Santo Domingo, you will need to run a search below.

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From $260 / RT details

Book your flight now with Cheapoair.com and save!

Cheap Santo Domingo airfares from $260/RT are provided by Cheapoair.com. Outbound flight is leaving on 03/10/2021, 01:36 pm from San Francisco Intl (SFO) airport and arrives at Santo Domingo Americas (SDQ) at 06:00 am. The flight time is 16 hours and 24 minutes. The Returning flight departes on 03/30/2021, 09:01 am (other return dates are also available). Date posted: 18 Oct 2020

Price evolution for flights From San Francisco To Santo Domingo

Price overview for flights from San Francisco to Santo Domingo

Recent Deals on Flights from San Francisco to Santo Domingo:Roundtrip / Oneway

  • $260Aeromexico flight Aeromexico 
    FromToDepartureTime
    San Francisco, CA (SFO)Santo Domingo, DO (SDQ)03/10/202101:36 pm
    Santo Domingo, DO (SDQ)San Francisco, CA (SFO)03/30/202109:01 am
    cheapoair.com check price
  • $284Aeromexico flight Aeromexico 
    FromToDepartureTime
    San Francisco, CA (SFO)Santo Domingo, DO (SDQ)03/03/202101:36 pm
    Santo Domingo, DO (SDQ)San Francisco, CA (SFO)03/09/202109:01 am
    cheapoair.com check price
  • $284Aeromexico flight Aeromexico 
    FromToDepartureTime
    San Francisco, CA (SFO)Santo Domingo, DO (SDQ)03/23/202102:36 pm
    Santo Domingo, DO (SDQ)San Francisco, CA (SFO)04/06/202108:01 am
    cheapoair.com check price
  • $505Copa Air flight Copa Air 
    FromToDepartureTime
    San Francisco, CA (SFO)Santo Domingo, DO (SDQ)03/10/202107:50 pm
    Santo Domingo, DO (SDQ)San Francisco, CA (SFO)03/30/202106:39 am
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  • $505Copa Air flight Copa Air 
    FromToDepartureTime
    San Francisco, CA (SFO)Santo Domingo, DO (SDQ)03/03/202107:50 pm
    Santo Domingo, DO (SDQ)San Francisco, CA (SFO)03/09/202106:39 am
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  • $285Copa Air flight Copa Air 
    FromToDepartureTime
    San Francisco, CA (SFO)Santo Domingo, DO (SDQ)12/26/202010:57 pm
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  • $285Copa Air flight Copa Air 
    FromToDepartureTime
    San Francisco, CA (SFO)Santo Domingo, DO (SDQ)12/16/202010:57 pm
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  • $285Copa Air flight Copa Air 
    FromToDepartureTime
    San Francisco, CA (SFO)Santo Domingo, DO (SDQ)11/30/202007:50 pm
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  • $376Jetblue Airways flight Jetblue Airways 
    FromToDepartureTime
    San Francisco, CA (SFO)Santo Domingo, DO (SDQ)11/30/202010:53 pm
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  • $485Jetblue Airways flight Jetblue Airways 
    FromToDepartureTime
    San Francisco, CA (SFO)Santo Domingo, DO (SDQ)12/26/202008:15 am
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Know what to do when flying to Santo Domingo?

Santo Domingo Travel Guide The city of Santo Domingo (also famous by the name of Santo Domingo de Guzmán) happens to be the capital city for the Dominican Republic. The city of Santo Domingo is situated somewhere around Caribbean Sea and the River Ozama is located [...]
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