Cheap flights from South Carolina to Detroit

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The New Detroit Science Center. This 110,000 square-foot building stands on 5020 John R Street. It was constructed for the purpose of scientific discoveries. It houses a Digital Imax Theater, a planetarium and exhibit laboratories.... (read more in our Detroit Sightseeing)

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Greenville/Spartanburg 

Check our newest flight offers to Detroit:

  • $300American Airlines flight American Airlines 
    FromToDepartureTime
    Spartanburg, SC (GSP)Detroit, MI (DTW)03/22/201706:00 am
    Detroit, MI (DTW)Spartanburg, SC (GSP)03/29/201706:05 am
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  • $318Southwest Airlines flight Southwest Airlines 
    FromToDepartureTime
    Spartanburg, SC (GSP)Detroit, MI (DTW)03/22/201706:50 am
    Detroit, MI (DTW)Spartanburg, SC (GSP)03/29/201707:20 am
    flyfar.ca check price
  • $319Southwest Airlines flight Southwest Airlines 
    FromToDepartureTime
    Spartanburg, SC (GSP)Detroit, MI (DTW)03/22/201706:50 am
    Detroit, MI (DTW)Spartanburg, SC (GSP)03/29/201707:20 am
    flightnetwork.com check price
  • $376American Airlines flight American Airlines 
    FromToDepartureTime
    Spartanburg, SC (GSP)Detroit, MI (DTW)03/22/201706:00 am
    Detroit, MI (DTW)Spartanburg, SC (GSP)03/30/201706:05 am
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  • $377Multiple Airlines flight Multiple Airlines 
    FromToDepartureTime
    Spartanburg, SC (GSP)Detroit, MI (DTW)03/22/201706:00 am
    Detroit, MI (DTW)Spartanburg, SC (GSP)03/30/201706:05 am
    travelgrove.com check price
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