Cheap flights from North Carolina to South America

Travel > South America

The history of Santa Cruz begins with a colonial settlement, as is the case with most South American cities. Spanish conquistador Nulfo de Chavez was the first to get there and to found a settlement on February 26, 1561. He named the city Santa Cruz de la Sierra (“Holy Cross of the Hills”) and continued his exploration through the jungles and rainforests in the territory. He also founded Buenos Aires and Asuncion, and the three cities grew to become important economical and... (read more in our Santa Cruz History)

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Check our newest flight offers to South America:

  • $473Jetblue Airways flight Jetblue Airways 
    FromToDepartureTime
    Durham, NC (RDU)Santiago, DO (STI)10/24/201707:00 am
    Santiago, DO (STI)Durham, NC (RDU)10/29/201701:01 pm
    cheapoair.com check price
  • $509Jetblue Airways flight Jetblue Airways 
    FromToDepartureTime
    Charlotte, NC (CLT)Santiago, DO (STI)10/20/201707:52 pm
    Santiago, DO (STI)Charlotte, NC (CLT)11/02/201709:09 am
    flighthub.com check price
  • $630United Airlines flight United Airlines 
    FromToDepartureTime
    Durham, NC (RDU)Lima, PE (LIM)11/10/201705:55 am
    Lima, PE (LIM)Durham, NC (RDU)11/23/201701:30 am
    flighthub.com check price
  • $868Copa Air flight Copa Air 
    FromToDepartureTime
    Charlotte, NC (CLT)Quito, EC (UIO)03/28/201806:00 am
    Quito, EC (UIO)Charlotte, NC (CLT)04/05/201803:13 pm
    flightnetwork.com check price
  • $1264Multiple Airlines flight Multiple Airlines 
    FromToDepartureTime
    Durham, NC (RDU)Santiago, CL (SCL)10/31/201702:35 pm
    Santiago, CL (SCL)Durham, NC (RDU)11/11/201707:45 pm
    flyfar.ca check price
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Multiple AirlinesMinneapolis To San Jose Multiple Airlines airfares from Minneapolis in November
$385 Depart: 11/05/2017
Return: 11/14/2017

provided by Flightnetwork

Jetblue AirwaysCharlotte To Detroit Jetblue Airways airfares from Charlotte in December
$606 Depart: 12/12/2017
Return: 12/27/2017

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Thy Turkish AirlinesAtlanta To Bari Thy Turkish Airlines airfares from Atlanta in May
$1094 Depart: 05/27/2017
Return: 06/03/2017

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Multiple AirlinesMaui To Richmond Multiple Airlines airfares from Maui in November
$893 Depart: 11/03/2017
Return: 11/12/2017

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Multiple AirlinesCincinnati To Omaha Multiple Airlines airfares from Cincinnati in November
$353 Depart: 11/01/2017
Return: 11/07/2017

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Jetblue AirwaysSacramento To Boston Jetblue Airways airfares from Sacramento in January
$379 Depart: 01/30/2018
Return: 02/13/2018

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United AirlinesColumbus To Washington DC United Airlines airfares from Columbus in November
$274 Depart: 11/26/2017
Return: 12/01/2017

provided by FlightHub

Copa AirChicago To Barranquilla Copa Air airfares from Chicago in December
$1882 Depart: 12/26/2017
Return: 01/07/2018

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United AirlinesPhoenix To Missoula United Airlines airfares from Phoenix in December
$633 Depart: 12/27/2017
Return: 01/03/2018

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