Cheap flights from Iowa to San Francisco

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The aggressive Spanish colonial expansion during the 18th century finally reached the shores of San Francisco Bay in 1769. An expedition led by Don Gaspar de Portola was credited for discovering San Francisco Bay, sighting it atop Sweeney Ridge, now a National Historic Landmark. A member of his crew, Sgt. Jose Francisco Ortega would later be identified as having discovered the strait now popularly known as the Golden Gate.... (read more in our San Francisco History)

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Des Moines 

Check our newest flight offers to San Francisco:

  • $278Frontier Airlines flight Frontier Airlines 
    FromToDepartureTime
    Des Moines, IA (DSM)San Francisco, CA (SFO)09/09/201708:00 pm
    San Francisco, CA (SFO)Des Moines, IA (DSM)09/20/201709:29 am
    cheapoair.com check price
  • $287Multiple Airlines flight Multiple Airlines 
    FromToDepartureTime
    Des Moines, IA (DSM)San Francisco, CA (SFO)09/09/201703:04 pm
    San Francisco, CA (SFO)Des Moines, IA (DSM)09/20/201708:55 am
    flyfar.ca check price
  • $288Multiple Airlines flight Multiple Airlines 
    FromToDepartureTime
    Des Moines, IA (DSM)San Francisco, CA (SFO)09/09/201703:04 pm
    San Francisco, CA (SFO)Des Moines, IA (DSM)09/20/201708:55 am
    flightnetwork.com check price
  • $295United Airlines flight United Airlines 
    FromToDepartureTime
    Des Moines, IA (DSM)San Francisco, CA (SFO)09/09/201703:04 pm
    San Francisco, CA (SFO)Des Moines, IA (DSM)09/20/201711:50 pm
    flighthub.com check price
  • $304United Airlines flight United Airlines 
    FromToDepartureTime
    Des Moines, IA (DSM)San Francisco, CA (SFO)09/09/201703:04 pm
    San Francisco, CA (SFO)Des Moines, IA (DSM)09/20/201711:50 pm
    flightnetwork.com check price
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