Cheap flights from Iowa to San Francisco

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The city of San Francisco, CA US is the 4th most populous county in California and 14th in the US. It is also one of the most popular nightlife spots in US and boasts everything ranging from opera, piano bars, theatres and ballets to hipster hangouts, Irish pubs, live music and cabaret.... (read more in our San Francisco Nightlife)

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Des Moines 

Check our newest flight offers to San Francisco:

  • $319Multiple Airlines flight Multiple Airlines 
    FromToDepartureTime
    Des Moines, IA (DSM)San Francisco, CA (SFO)04/25/202106:44 pm
    San Francisco, CA (SFO)Des Moines, IA (DSM)05/06/202103:35 pm
    cheapoair.com check price
  • $321Multiple Airlines flight Multiple Airlines 
    FromToDepartureTime
    Des Moines, IA (DSM)San Francisco, CA (SFO)05/15/202110:53 am
    San Francisco, CA (SFO)Des Moines, IA (DSM)05/20/202112:59 am
    cheapoair.com check price
  • $377Alaska Airlines flight Alaska Airlines 
    FromToDepartureTime
    Des Moines, IA (DSM)San Francisco, CA (SFO)05/15/202110:53 am
    San Francisco, CA (SFO)Des Moines, IA (DSM)05/20/202107:00 am
    cheapoair.com check price
  • $447Alaska Airlines flight Alaska Airlines 
    FromToDepartureTime
    Des Moines, IA (DSM)San Francisco, CA (SFO)04/25/202102:45 pm
    San Francisco, CA (SFO)Des Moines, IA (DSM)05/06/202103:35 pm
    cheapoair.com check price
  • $450Alaska Airlines flight Alaska Airlines 
    FromToDepartureTime
    Des Moines, IA (DSM)San Francisco, CA (SFO)05/14/202112:45 pm
    San Francisco, CA (SFO)Des Moines, IA (DSM)05/26/202107:00 am
    cheapoair.com check price
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